asymmetric aza-米乐app官方

the asymmetric aza-henry reaction of α-substituted nitroacetates and n-boc imines was achieved with a new-type thiourea-guanidine bifunctional organocatalyst. the novel transformations exhibited high diastereoselectivities, and the adducts bearing adjacent quaternary and tertiary chiral centers were generally obtained in moderate to good enantioselectivities (up to 88% ee).